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Acanthosis nigricans is a cutaneous manifestation of an underlying condition. It develops in skin folds, such as the back of the neck, axilla, and groin, where it presents as velvety hyper-pigmented patches with poorly defined borders.
EtiologyFamilial acanthosis nigricans:Obesity-associated acanthosis nigricansMedications associated with acanthosis nigricansAcanthosis nigricans associated with endocrine ( diabetes and insulin resistance)Acral acanthotic anomaly:Malignant acanthosis nigricans syndromeAuto-immune acanthosis nigricans:Unilateral acanthosis nigrican